| Date | heure | Visiteur | Score | Domicile |
| Semaine 1 | ||||
| Jeudi 7 septembre | 2h30 | Dallas Cowboys | New York Giants | |
| Dimanche 9 septembre | 19h | Indianapolis Colts | Chicago Bears | |
| 19h | Jacksonville Jaguars | Minnesota Vikings | ||
| 19h | Buffalo Bills | New York Jets | ||
| 19h | Miami Dolphins | Houston Texans | ||
| 19h | New England Patriots | Tennessee Titans | ||
| 19h | Saint Louis Rams | Detroit Lions | ||
| 19h | Washington Redskins | New Orleans Saints | ||
| 19h | Philadelphia Eagles | Cleveland Browns | ||
| 19h | Atlanta Falcons | Kansas City Chiefs | ||
| 22h15 | San Francisco 49ers | Green Bay Packers | ||
| 22h15 | Seattle Seahawks | Arizona Cardinals | ||
| 22h15 | Carolina Panthers | Tampa Bay Buccaneers | ||
| Lundi 10 septembre | 2h20 | Pittsburgh Steelers | Denver Broncos | |
| Mardi 11 septembre | 1h | Cincinnati Bengals | Baltimore Ravens | |
| 4h15 | San Diego Chargers | Oakland Raiders | ||
| Semaine 2 | ||||
| Vendredi 14 septembre | 2h20 | Chicago Bears | Green Bay Packers | |
| Dimanche 16 septembre | 19h | Tampa Bay Buccaneers | New York Giants | |
| 19h | New Orleans Saints | Carolina Panthers | ||
| 19h | Arizona Cardinals | New England Patriots | ||
| 19h | Minnesota Vikings | Indianapolis Colts | ||
| 19h | Baltimore Ravens | Philadelphia Eagles | ||
| 19h | Kansas City Chiefs | Buffalo Bills | ||
| 19h | Cleveland Browns | Cincinnati Bengals | ||
| 19h | Houston Texans | Jacksonville Jaguars | ||
| 22h05 | Dallas Cowboys | Seattle Seahawks | ||
| 22h05 | Washington Redskins | Saint Louis Rams | ||
| 22h15 | New York Jets | Pittsburgh Steelers | ||
| 22h15 | Tennessee Titans | San Diego Chargers | ||
| 22h15 | Oakland Raiders | Miami Dolphins | ||
| Lundi 17 septembre | 2h20 | Detroit Lions | San Francisco 49ers | |
| Mardi 18 Septembre | 2h30 | Denver Broncso | Atlanta Falcons | |
| Semaine 3 | ||||
| Vendredi 21 septembre | 2h | New York Giants | Carolina Panthers | |
| Dimanche 23 septembre | 19h | Tampa Bay Buccaneers | Dallas Cowboys | |
| 19h | Saint Louis Rams | Chicago Bears | ||
| 19h | San Francisco 49ers | Minnesota Vikings | ||
| 19h | Detroit Lions | Tennessee Titans | ||
| 19h | Cincinnati Bengals | Washington Redskins | ||
| 19h | Kansas City Chiefs | New Orleans Saints | ||
| 19h | New York Jets | Miami Dolphins | ||
| 19h | Buffalo Bills | Cleveland Browns | ||
| 19h | Jacksonville Jaguars | Indianapolis Colts | ||
| 22h05 | Philadelphia Eagles | Arizona Cardinals | ||
| 22h05 | Atlanta Falcons | San Diego Chargers | ||
| 22h15 | Houston Texans | Denver Broncos | ||
| 22h15 | Pittsburgh Steelers | Oakland Raiders | ||
| Lundi 24 septembre | 2h20 | New England Patriots | Baltimore Ravens | |
| Mardi 25 septembre | 2h30 | Green Bay Packers | Seattle Seahawks | |
| Semaine 4 | ||||
| Vendredi 28 septembre | 2h20 | Cleveland Browns | Baltimore Ravens | |
| Dimanche 30 septembre | 19h | New England Patriots | Buffalo Bills | |
| 19h | Tennessee Titans | Houston Texans | ||
| 19h | San Diego Chargers | Kansas City Chiefs | ||
| 19h | Minnesota Vikings | Detroit Lions | ||
| 19h | Carolina Panthers | Atlanta Falcons | ||
| 19h | Seattle Seahawks | Saint Louis Rams | ||
| 19h | San Francisco 49ers | New York Jets | ||
| 22h05 | Miami Dolphins | Arizona Cardinals | ||
| 22h05 | Oakland Raiders | Denver Broncos | ||
| 22h05 | Cincinnati Bengals | Jacksonville Jaguars | ||
| 22h15 | New Orleans Saints | Green Bay Packers | ||
| 22h15 | Washington Redskins | Tampa Bay Buccaneers | ||
| Lundi 1 octobre | 2h20 | New York Giants | Philadelphia Eagles | |
| Mardi 2 octobre | 2h30 | Chicago Bears | Dallas Cowboys | |
| Semaine 5 | ||||
| Vendredi 5 octobre | 2h20 | Arizona Cardinals | Saint Louis Rams | |
| Dimanche 7 octobre | 19h | Atlanta Falcons | Washington Redskins | |
| 19h | Philadelphia Eagles | Pittsburgh Steelers | ||
| 19h | Green Bay Packers | Indianapolis Colts | ||
| 19h | Cleveland Browns | New York Giants | ||
| 19h | Miami Dolphins | Cincinnati Bengals | ||
| 19h | Baltimore Ravens | Kansas City Chiefs | ||
| 22h05 | Seattle Seahawks | Carolina Panthers | ||
| 22h05 | Chicago Bears | Jacksonville Jaguars | ||
| 22h15 | Tennessee Titans | Minnesota Vikings | ||
| 22h15 | Denver Broncos | New England Patriots | ||
| 22h15 | Buffalo Bills | San Francisco 49ers | ||
| Lundi 8 octobre | 2h20 | San Diego Chargers | New Orleans Saints | |
| Mardi 9 octobre | 2h30 | Houston Texans | New York Jets | |
| Semaine 6 | ||||
| Vendredi 12 octobre | 2h20 | Pittsburgh Steelers | Tennessee Titans | |
| Dimanche 14 octobre | 19h | Oakland Raiders | Atlanta Falcons | |
| 19h | Kansas City Chiefs | Tampa Bay Buccaneers | ||
| 19h | Indianapolis Colts | New York Jets | ||
| 19h | Cincinnati Bengals | Cleveland Browns | ||
| 19h | Detroit Lions | Philadelphia Eagles | ||
| 19h | Saint Louis Rams | Miami Dolphins | ||
| 19h | Dallas Cowboys | Baltimore Ravens | ||
| 22h05 | Buffalo Bills | Arizona Cardinals | ||
| 22h05 | New England Patriots | Seattle Seahawks | ||
| 22h15 | New York Giants | San Francisco 49ers | ||
| 22h15 | Minnesota Vikings | Washington Redskins | ||
| Lundi 15 octobre | 2h20 | Green Bay Packers | Houston Texans | |
| Mardi 16 octobre | 2h30 | Denver Broncos | San Diego Chargers | |
| Semaine 7 | ||||
| Vendredi 19 octobre | 2h20 | Seattle Seahawks | San Francisco 49ers | |
| Dimanche 21 octobre | 19h | Washington Redskins | New York Giants | |
| 19h | Dallas Cowboys | Carolina Panthers | ||
| 19h | Arizona Cardinals | Minnesota Vikings | ||
| 19h | New Orleans Saints | Tampa Bay Buccaneers | ||
| 19h | Green Bay Packers | Saint Louis Rams | ||
| 19h | Baltimore Ravens | Houston Texans | ||
| 19h | Cleveland Browns | Indianpolis Colts | ||
| 19h | Tennessee Titans | Buffalo Bills | ||
| 22h15 | New York Jets | New England Patriots | ||
| 22h15 | Jacksonville Jaguars | Oakland Raiers | ||
| Lundi 22 octobre | 2h20 | Pittsburgh Steelers | Cincinnati Bengals | |
| Mardi 23 octobre | 2h30 | Detroit Lions | Chicago Bears | |
| Semaine 8 | ||||
| Vendredi 26 octobre | 2h20 | Tampa Bay Buccaneers | Minnesota Vikings | |
| Dimanche 28 octobre | 19h | Jacksonville Jaguars | Green Bay Packers | |
| 19h | Miami Dolphins | New York Jets | ||
| 19h | San Diego Chargers | Cleveland Browns | ||
| 19h | Indianapolis COlts | Tennessee Titans | ||
| 19h | New England Patriots | Saint Louis Rams | ||
| 19h | Atlanta Falcons | Philadelphia Eagles | ||
| 19h | Carolina Panthers | Chicago Bears | ||
| 19h | Seattle Seahawks | Detroit Lions | ||
| 19h | Washington Redskins | Pittsburgh Steelers | ||
| 22h05 | Oakland Raiders | Kansas City Chiefs | ||
| 22h15 | New York Giants | Dalas Cowboys | ||
| Lundi 29 octobre | 2h20 | New Orleans Saints | Denver Broncos | |
| Mardi 30 octobre | 2h30 | San Francisco 49ers | Arizona Cardinals | |
| Semaine 9 | ||||
| Vendredi 2 novembre | 19h | Kansas City Chiefs | San Diego Chargers | |
| Dimanche 4 novembre | 19h | Carolina Panthers | Washington Redskins | |
| 19h | Arizona Cardinals | Green Bay Packers | ||
| 19h | Detroit Lions | Jacksonville Jaguars | ||
| 19h | Chicago Bears | Tennessee Titans | ||
| 19h | Denver Broncos | Cincinnati Bengals | ||
| 19h | Baltimore Ravens | Cleveland Browns | ||
| 19h | Buffalo Bills | Houston Texans | ||
| 19h | Miami Dolphins | Indianapolis C0lts | ||
| 22h05 | Minnesota Vikings | Seattle Seahawks | ||
| 22h05 | Tampa Bay Buccaneers | Oakland Raiders | ||
| 22h15 | Pittsburgh Steelers | New York Giants | ||
| Lundi 5 novembre | 2h20 | Dallas Cowboys | Atlanta Falcons | |
| Mardi 6 novembre | 2h30 | Phladelphia Eagles | New Orleans Saints | |
| Semaine 10 | ||||
| Vendredi 9 novembre | 2h20 | Indianapolis Colts | Jacksonville Jaguars | |
| Dimanche 11 novembre | 19h | Denver Broncos | Carolina Panthers | |
| 19h | San Diego Chargers | Tampa Bay Buccaneers | ||
| 19h | Tennessee Titans | Miami Dolphins | ||
| 19h | Buffalo Bills | New England Patriots | ||
| 19h | Oakland Raiders | Baltimore Ravens | ||
| 19h | New York Giants | Cincinnati Bengals | ||
| 19h | Atlanta Falcons | New Orleans Saints | ||
| 19h | Detroit Lions | Minnesota Vikings | ||
| 22h05 | New York Jets | Seattle Seahawks | ||
| 22h15 | Dallas Cowboys | Philadelphia Eagles | ||
| 22h15 | Saint Louis Rams | San Francisco 49ers | ||
| Lundi 12 novembre | 2h20 | Houston Texans | Chicago Bears | |
| Mardi 13 novembre | 2h30 | Kansas City Chiefs | Pittsburgh Steelers | |
| Semaine 11 | ||||
| Vendredi 16 novembre | 2h20 | Miami Dolphins | Buffalo Bills | |
| Dimanche 18 novembre | 19h | Philadelphia Eagles | Washington Redskins | |
| 19h | Green Bay Packers | Detroit Lions | ||
| 19h | Arizona Cardinals | Atlanta Falcons | ||
| 19h | Tampa Bay Buccaneers | Carolina Panthers | ||
| 19h | Cleveland Browns | Dallas Cowboys | ||
| 19h | New York Jets | Saint Louis Rams | ||
| 19h | Indianapolis Colts | New England Patriots | ||
| 19h | Jacksonville Jaguars | Houston Texans | ||
| 19h | Cincinnati Bengals | Kansas City Chiefs | ||
| 22h05 | New Orleans Saints | Oakland Raiders | ||
| 22h15 | San Diego Chargers | Denver Broncos | ||
| Lundi 19 novembre | 2h20 | Baltimore Ravens | Pittsburgh Steelers | |
| Mardi 20 novembre | 2h30 | Chicago Bears | San Francisco 49ers | |
| Semaine 12 | ||||
| Jeudi 22 novembre | 18h30 | Houston Texans | Detroit Lions | |
| 22h15 | Washington Redskins | Dallas Cowboys | ||
| Vendredi 23 novembre | 2h20 | New England Patriots | New York Jets | |
| Dimanche 25 novembre | 19h | Oakland Raiders | Cincinnati Bengals | |
| 19h | Pittsburgh Steelers | Cleveland Browns | ||
| 19h | Buffalo Bills | Indianapolis Colts | ||
| 19h | Tennessee Titans | Jacksonville Jaguars | ||
| 19h | Denver Broncos | Kansas City Chiefs | ||
| 19h | Minnesota Vikings | Chicago Bears | ||
| 19h | Atlanta Falcons | Tampa Bay Buccaneers | ||
| 19h | Seattle Seahawks | Miami Dolphins | ||
| 22h05 | Baltimore Ravens | San Diego Chargers | ||
| 22h15 | San Francisco 49ers | New Orleans Saints | ||
| 22h15 | Saint Louis Rams | Arizona Cardinals | ||
| Lundi 26 novembre | 2h20 | Green Bay Packers | New York Giants | |
| Mardi 27 novembre | 2h30 | Carolina Panthers | Philadelphia Eagles | |
| Semaine 13 | ||||
| Vendredi 30 novembre | 2h20 | New Orleans Saints | Atlanta Falcons | |
| Dimanche 2 décembre | 19h | Seattle Seahawks | Chicago Bears | |
| 19h | Minnesota Vikings | Green Bay Packers | ||
| 19h | San Francisco 49ers | Saint Louis Rams | ||
| 19h | Arizona Cardinals | New York Jets | ||
| 19h | Carolina Panthers | Kansas City Chiefs | ||
| 19h | Indianapolis Colts | Detroit Lions | ||
| 19h | Jacksonville Jaguars | Buffalo Bills | ||
| 19h | New England Patriots | Miami Dolphins | ||
| 19h | Houston Texans | Tennessee Titans | ||
| 22h05 | Tampa Bay Buccaneers | Denver Broncos | ||
| 22h15 | Pittsburgh Steelers | Baltimore Ravens | ||
| 22h15 | Cleveland Browns | Oakland Raiders | ||
| 22h15 | Cincinnati Bengals | San Diego Chargers | ||
| Lundi 3 décembre | 2h20 | Philadelphia Eagles | Dallas Cowboys | |
| Mardi 4 décembre | 2h30 | New York Giants | Washington Redskins | |
| Semaine 14 | ||||
| Vendredi 7 décembre | 2h20 | Denver Broncos | Oakland Raiders | |
| Dimanche 9 décembre | 19h | Baltimore Ravens | Washington Redskins | |
| 19h | Kansas City Chiefs | Cleveland Browns | ||
| 19h | San Diego Chargers | Pittsburgh Steelers | ||
| 19h | Tennessee Titans | Indianapolis Colts | ||
| 19h | New York Jets | Jacksonville Jaguars | ||
| 19h | Chicago Bears | Minnesota Vikings | ||
| 19h | Atlanta Falcons | Carolina Panthers | ||
| 19h | Philadelphia Eagles | Tampa Bay Buccaneers | ||
| 19h | Saints Louis Rams | Buffalo Bills | ||
| 19h | Dallas Cowboys | Cincinnati Bengals | ||
| 22h05 | Miami Dolphins | San Francisco 49ers | ||
| 22h15 | New Orleans Saints | New York Giants | ||
| 22h15 | Arizona Cardinals | Seattle Seahawks | ||
| Lundi 10 décembre | 2h20 | Detroit Lions | Green Bay Packers | |
| Mardi 11 décembre | 2h30 | Houston Texans | New England Patriots | |
| Semaine 15 | ||||
| Vendredi 14 décembre | 2h20 | Cincinnati Bengals | Philadelphia Eagles | |
| Dimanche 16 décembre | 19h | Green Bay Packers | Chicago Bears | |
| 19h | Tampa Bay Buccaneers | New Orleans Saints | ||
| 19h | Minnesota Vikings | Saint Louis Rams | ||
| 19h | New York Giants | Atlanta Falcons | ||
| 19h | Washington Redskins | Cleveland Browns | ||
| 19h | Jacksonville Jaguars | Miami Dolphins | ||
| 19h | Denver Broncos | Baltimore Ravens | ||
| 19h | Indianapolis Colts | Houston Texans | ||
| 22h05 | Detroit Lions | Arizona Cardinals | ||
| 22h05 | Carolina Panthers | San Diego Chargers | ||
| 22h05 | Seattle Seahawks | Buffalo Bills | ||
| 22h15 | Pittsburgh Steelers | Dallas Cowboys | ||
| 22h15 | Kansas City Chiefs | Oakland Raiders | ||
| Lundi 17 décembre | 2h20 | San Francisco 49ers | New England Patriots | |
| Mardi 18 décembre | 2h30 | New York Jets | Tennessee Titans | |
| Semaine 16 | ||||
| Dimanche 23 décembre | 2h20 | Atlanta Falcons | Detroit Lions | |
| 19h | Tennessee Titans | Green Bay Packers | ||
| 19h | Oakland Raiders | Carolina Panthers | ||
| 19h | Buffalo Bills | Miami Dolphins | ||
| 19h | Cincinnati Bengals | Pittsburgh Steelers | ||
| 19h | New England Patriots | Jacksonville Jaguars | ||
| 19h | Indianapolis Colts | Kansas City Chiefs | ||
| 19h | New Orleans Saints | Dallas Cowboys | ||
| 19h | Washington Redskins | Philadelphia Eagles | ||
| 19h | Saint Louis Rams | Tampa Bay Buccaneers | ||
| 19h | New York Giants | Baltimore Ravens | ||
| 19h | Minnesota Vikings | Houston Texans | ||
| 22h05 | Cleveland Browns | Denver Broncos | ||
| 22h15 | Chicago Bears | Arizona Cardinals | ||
| 22h15 | San Francisco 49ers | Seattle Seahawks | ||
| Lundi 24 décembre | 2h20 | San Diego Chargers | New York Jets | |
| Semaine 17 | ||||
| Dimanche 30 janvier | 19h | New York Jets | Buffalo Bills | |
| 19h | Miami Dolphins | New England Patriots | ||
| 19h | Baltimore Ravens | Cincinnati Bengals | ||
| 19h | Cleveland Browns | Pittsburgh Steelers | ||
| 19h | Houston Texans | Indianapolis Colts | ||
| 19h | Jacksonville Jaguars | Tennessee Titans | ||
| 19h | Philadelphia Eagles | New York Giants | ||
| 19h | Dallas Cowboys | Washington Redskins | ||
| 19h | Chicago Bears | Detroit Lions | ||
| 19h | Green Bay Packers | Minnesota Vikings | ||
| 19h | Tampa Bay Buccaneers | Atlanta Falcons | ||
| 19h | Carolina Panthers | New Orleans Saints | ||
| 22h15 | Kansas City Chiefs | Denver Broncos | ||
| 22h15 | Oakland Raiders | San Diego Chargers | ||
| 22h15 | Arizona Cardinals | San Francisco 49ers | ||
| 22h15 | Saint Louis Rams | Seattle Seahawks |
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